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Vetsulin (porcine insulin zinc suspension)

Vetsulin (called Caninsulin in Canada)

Also known as: Caninsulin

Pet Size

Don't know your pet's weight?

If you can't get them on the scale, try this super simple method:

  1. Weigh yourself.
  2. Weigh yourself holding your pet.
  3. Subtract the two numbers to get their weight.

Too heavy to hold? Your vet will weigh them if you ask (or may already have it on file if you call).


No Prescription Required

  • Description

    Manufactured by Merck

    Vetsulin is a pet insulin for animals who have diabetes mellitus (sugar diabetes) and the elevated blood glucose levels that are a long-term health risk for pets in the same way they are for humans. Vetsulin is an injectable insulin suspension that can bring down blood sugar levels in pets quickly when the animal has hyperglycemia. Vetsulin is an FDA-approved pet injection that controls glucose levels and lessens the signs of diabetes in pets, including frequent urination, increased thirst, constant hunger, weight loss, cloudy eyes, lethargy, or hypersomnolence (excessive sleeping).


    Be sure you are administering the correct Vetsulin dosage based on your veterinarian's instruction and what is indicated in the prescription you have for your pet

    Wash your hands before handling medication or administering it

    Remove vial of Vetsulin from refrigerator and shake vial until the pet insulin has a milky consistency to it and any foam is completely dispersed

    Remove cap from the needle and insert the needle into the vial

    Turn vial upside down while still ensuring the tip of the needle remains in the vial

    Draw the correct dose into the U-40 syringe

    Inspect the syringe to determine there are no air bubbles. If bubbles are seen you can eliminate them by holding the syringe up and tapping the side of it until the bubbles move the top. Push them out using the plunger and then draw the correct dose again.

    Remove needle from vial


    Pinch a fold of your pet's skin.

    Administer the injection subcutaneously, at a point that 3/4 of an inch to 2 inches from the dorsal midline, and varying from behind the scapulae to the mid lumbar region and alternating sides. Your veterinarian may specify a different injection site based on your pet.

    Press down plunger as far as it will go. Confirm solution has been fully injected from syringe and then place vial back in the refrigerator.


    The active ingredient in Vetsulin is Porcine Insulin Zinc Solution


    Vetsulin is to be injected with a U-40 syringe only. Using any other type of syringe could result in incorrect dosing and serious harm or even death occurring to the pet

    Never dilute Vetsulin

    Pet insulin should be refrigerated (do not freeze) and kept out of direct light

    Vials that are exposed to high heat or frozen must be discarded

    Contents of vial not administered should be discarded after 42 days of vial first being punctured

    It is important that you pet eats before you administer Vetsulin

    Syringes should be disposed of properly in a Sharps container


    There is the possibility of negative drug interactions between Vetsulin and other Rx medications, including prescription drugs for pets classified as antimicrobials, antivirals, antifungals, antihistamines, analgesics, anesthetics/tranquilizers, diuretics, bronchodilators, corticosteroids (cats), NSAIDs, thyroid hormone supplementation, hyperthyroid medication (methimazole), internal and external parasiticides, anti-emetics, dermatological topical treatments and oral supplements, and ophthalmic preparations containing antimicrobials and anti-inflammatory medications.

    Vaccines may also present interaction risks. Tell your veterinarian of all medications your pet is currently taking before getting prescription and proceeding to buy Vetsulin.

    Side Effects

    Vetsulin side effects are a possibility, and some pets may experience vomiting, diarrhea, weight loss or appetite loss, or development of urinary tract infections. If these side effects are seen it may be best to discontinue use until you are able to meet with a veterinarian and discuss other pet insulin alternatives or a different approach to treating pet diabetes.

    Frequently Asked Questions about Vetsulin

    What is Vetsulin?

    Vetsulin is an FDA-approved insulin used to manage diabetes mellitus in both dogs and cats.

    What type of insulin is Vetsulin?

    Vetsulin is an intermediate-acting, lente insulin containing 40 IU/mL of highly purified porcine insulin. It consists of 35% amorphous and 65% crystalline zinc insulin.

    How does Vetsulin work?

    Vetsulin has a rapid onset of activity, usually peaking around 4 hours after injection and lasting for 8 hours. The remaining crystalline insulin component is absorbed more slowly and peaks around 11 hours after administration.

    How long does it take for Vetsulin to start working?

    In cats, the peak activity occurs between 1.5 and 8 hours (with an average of about 4 hours), and the duration of activity varies between 8 and 12 hours.

    Does Vetsulin need to be refrigerated?

    Yes, Vetsulin must be refrigerated before first use. Store it at a temperature between 36°F and 46°F (2°C and 8°C) to maintain its effectiveness and safety.

    How long can Vetsulin be out of the fridge?

    Contents of Vetsulin vials and cartridges should be used within 42 days of first puncture.

    How long does Vetsulin last?

    Vetsulin generally has a duration of activity ranging from 14 to 24 hours in dogs and 8 to 12 hours in cats.

    Is Vetsulin prescription only?

    Yes, Vetsulin is available only by prescription. Always consult your veterinarian for proper usage and dosing.

    Product Code : 13371