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Heartgard Plus

Heartgard Plus (Ivermectin / Pyrantel)

Pet Size

Don't know your pet's weight?

If you can't get them on the scale, try this super simple method:

  1. Weigh yourself.
  2. Weigh yourself holding your pet.
  3. Subtract the two numbers to get their weight.

Too heavy to hold? Your vet will weigh them if you ask (or may already have it on file if you call).


No Prescription Required

  • Description

    Heartgard Plus is heartworm prevention medication for dogs that’s in a chewable beef-flavoured tablet that dogs love. It defends against heartworm infections dogs can get when they are bitten by mosquitoes - something that is difficult to prevent if your dog is outdoors regularly. Heartgard Plus is a very valuable resource for these pet owners because if left unchecked heartworm disease can eventually be fatal for the dog. Fortunately, Heartgard Plus chewable provides year-round protection against heartworm disease when taken just once a month.

    Buy Heartgard Plus chewable from World Pet Express and count on the best price for this effective heartworm medication.


    Dogs usually eat Heartgard Plus chewable as soon as you offer them as they’re about as tasty as can be for a dog. You can very likely feed them to him or her by hand, but if not then the alternative is to mix the chewable into wet dog food and have them ingest this anti-heartworm medication that way.

    Just one chewable per month 12 times a year means your dog is going to be reliably protected against heartworm disease.


    The active ingredients in Heartgard are Ivermectin and Pyrantel Pamoate.


    Heartgard Plus Chewables are a safe heartworm killer medication for dogs, but it is best to still adhere to certain precaution when giving it to your pet. For starters, all dogs should be tested for heartworm infection before starting a preventive program.

    Never give your pet more than one chewable per month, even if you have concerns about the effectiveness of it or not. Heartgard Plus contains melosomine dihydrochloride, a compound that can be toxic in elevated amounts. For this reason, you must not give your pet more than one chewable a month.

    In addition, Heartgard Plus should not be taken concurrently with any other heartworm medication for dogs.


     Heartgard Plus is FDA and EPA approved, and no interaction risks with any other medication or supplement products have been documented.

    Side Effects

    Most pets will not experience side effects when taking Heartgard Plus for dogs as part of a heartworm prevention approach. However, some side effects may be possible and they include:

    • - Depression/lethargy
    • - Vomiting
    • - Anorexia
    • - Diarrhea

    Frequently Asked Questions about Heartgard Plus

    What is Heartgard Plus?

    Heartgard Plus is a medication used for heartworm prevention in dogs. It eliminates heartworm larvae that infected the dog in the month (30 days) before treatment. It also controls heartworm infections acquired in the previous 4 months, provided monthly treatment is continued for at least 12 months.

    Does Heartgard Plus kill fleas?

    No, Heartgard Plus does not kill fleas. It is primarily used for heartworm prevention and also treats and controls roundworms and hookworms. While it’s essential to address fleas, Heartgard Plus focuses on heartworms and other internal parasites.

    How often to give Heartgard Plus?

    Give your dog a Heartgard Plus chew once a month, year-round. It’s crucial to maintain regular dosing to ensure continuous protection against heartworm disease and other parasites.

    Is Heartgard Plus safe for dogs?

    Yes, Heartgard Plus is safe to use in all dogs aged 6 weeks and older. It has shown a wide margin of safety, including pregnant or breeding bitches, stud dogs, and puppies aged 6 weeks or more.

    Does Heartgard Plus need a prescription?

    Yes, your dog will need an annual negative heartworm test and a prescription from your licensed veterinarian to obtain Heartgard Plus. It’s essential to consult with your vet for proper administration and protection.

    Do dogs really need Heartgard every month?

    Yes, consistent monthly dosing of Heartgard Plus is crucial. Heartworm larvae can be transmitted by mosquitoes, so maintaining regular treatment helps prevent heartworm disease.

    Why is Heartgard so expensive?

    The cost of Heartgard reflects its effectiveness, safety, and quality. It’s a well-researched and trusted product that provides essential protection against heartworms and other parasites.

    Do dogs need Heartgard in winter?

    Yes, dogs should continue receiving Heartgard Plus even during winter. Heartworm transmission can occur year-round, especially in regions with mild climates. Consistent dosing ensures continuous protection.

    Can I skip a month of Heartgard?

    It’s not recommended to skip doses. Regular administration is essential for effective heartworm prevention. If you miss a dose, consult your veterinarian for guidance.

    Can Heartgard make a dog sick?

    While Heartgard Plus is generally safe, some dogs may experience mild digestive or neurologic side effects. Always follow proper dosing guidelines and consult your vet if you have concerns.

    Product Code : 9626