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Frontline Plus for Dogs

Frontline Plus

Also known as: Frontline Combo

Pet Size

Don't know your pet's weight?

If you can't get them on the scale, try this super simple method:

  1. Weigh yourself.
  2. Weigh yourself holding your pet.
  3. Subtract the two numbers to get their weight.

Too heavy to hold? Your vet will weigh them if you ask (or may already have it on file if you call).


No Prescription Required

  • Description

    Frontline Plus is an effective flea and ticks medication available in separate formulas for dogs and cats, and it also kills chewing lice. This topical flea killer not only kills the fleas and ticks themselves, but it also put an end to flea eggs and larvae so that the chances of your pet having a resurgence of the parasites are very small. A single treatment with either Frontline Plus for dogs or Frontline Plus for cats provides a full month of defence against these unwelcome guests and applying this quality flea medication for pets couldn’t be any easier.

    Buy Frontline Plus online from World Pet Express and get the best price on it always.


    Start by removing the applicator from the Frontline Plus package. Hold the foil upward and then snap off the tip of the applicator. Now spread your pet's fur at the base of its neck so that the skin underneath is exposed. Dispense the entirety of each dose on the skin and allow it to spread over the area. Do not use your fingers or any other implement to spread it, it will spread on its own. Do not make contact or allow any other animal in the home to make contact with the area until it has dried. Wait 24 hours until bathing your pet or allowing them to swim or become wet.

    • Frontline Plus for Cats over 1.5 lbs (Green)

    • Frontline Plus for Small Dogs up to 22lbs (Orange)

    • Frontline Plus for Medium Dogs 23-44 lbs (Blue)

    • Frontline Plus for Large Dogs 45-88 lbs (Purple)

    • Frontline Plus for Extra Large Dogs over 89 lbs (Red)


    The active ingredients in Frontline Plus are Fipronil and (S)-Methoprene


    Frontline Plus is an effective flea and tick medication for pets, but it is only to be used for animals that are ages 8 weeks and up. In addition, this medication is only for use with animals and should be kept out of the reach of children.

    Owners should not exceed the once-a-month application guideline for this flea and tick topical solution. If it appears to be less effective than expected, you should have a follow-up appointment with your veterinarian.


    While there are no known contraindications or known interactions between Frontline Plus and any drugs or other pet health supplements, it is advisable to disclose all medications your pet is currently taking when discussing the use of Frontline Plus with your physician prior to him or her writing you a prescription for it.

    Side Effects

    Use of Frontline Plus for dogs or Frontline Plus for cats may result in the hair loss, itching and skin redness.

    But these side effects are seen as being very uncommon. In the rarest of instances pets have experienced neurological issues like uncoordinated movement and lethargy, but any concerns you have regarding this can be discussed with your veterinarian.

    Frequently Asked Questions about Frontline Plus for Dogs

    How to apply Frontline Plus for dogs?

    Open the package and squeeze all the contents onto the skin between your dog’s shoulders, ensuring it reaches the skin.

    Does Frontline Plus expire?

    Frontline Plus has an expiration date of one year from the date of manufacture. It remains effective within this timeframe.

    How long does it take Frontline Plus to work?

    Frontline Plus starts killing fleas within 18 hours and eliminates ticks within 48 hours of application.

    How does Frontline Plus work?

    Frontline Plus contains two active ingredients: fipronil (kills adult fleas and ticks) and s-methoprene (prevents flea eggs and larvae from maturing). It disrupts the flea life cycle and provides month-long protection.

    Is Frontline Plus safe for dogs?

    The active ingredients in Frontline Plus, fipronil and s-methoprene, are considered safe and effective for most dogs.

    How long does Frontline Plus last?

    A single dose of Frontline Plus provides protection for 30 days against fleas, ticks, and lice.

    Is Frontline Plus safe for cats?

    Frontline Plus is generally safe for cats, but always follow proper application guidelines and consult your vet if you have concerns.

    Does Frontline Plus kill ear mites?

    Frontline Plus primarily targets fleas, ticks, and lice. It is not specifically designed to kill ear mites.

    How long does Frontline Plus take to dry?

    Allow the application area to dry after applying Frontline Plus. Avoid bathing your dog for at least a day.

    Can Frontline Plus for dogs be used on cats?

    No, Frontline Plus for dogs should not be used on cats. Use cat-specific products for feline protection.

    Product Code : 2557