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Credelio Plus (Lotilaner+Milbemycin Oxime)

Pet Size

Don't know your pet's weight?

If you can't get them on the scale, try this super simple method:

  1. Weigh yourself.
  2. Weigh yourself holding your pet.
  3. Subtract the two numbers to get their weight.

Too heavy to hold? Your vet will weigh them if you ask (or may already have it on file if you call).


No Prescription Required

  • Description

    Credelio Plus is a prescription flea and tick medication for dogs that also prevents heartworms and other parasitic worms like hookworms, whipworms, and roundworms. This makes it an all-in-one parasite protection solution that requires nothing more from dog owners than giving their pet one of the flavored chewable flea and tick killer tablets once a month. The first active ingredient, Lotaliner, is absorbed into the bloodstream and kills fleas and ticks when they bite the animal. The second, Milbemycin oxime, is metabolized in the large intestine and kills worms there as they attempt to establish themselves in the larval stage.

    You can buy Credelio Plus with a prescription, and your best Credelio Plus price will be when your order it from World Pet Express.


    Give your pet one Credelio plus chewable once a month, and at the same time each month. Administer Credelio Plus with food or within 30 minutes of feeding to allow for the dog having peak blood levels and exposure.


    The active ingredients in Credelio Plus are Lotaliner and Milbemycin Oxime.


    Credelio Plus may not be suitable for dogs with a history of seizures or neurologic disorders, and this is something that should be discussed with your veterinarian before getting a prescription or starting on this flea, tick, and worm killer medication for dogs.

    Use of Credelio Plus may not be suitable for some breeds of dogs because of increased sensitivity to Milbemycin Oxime, and among them are collies, sheepdogs, and collie- or sheepdog-cross breeds. Your veterinarian will be able to discuss this in greater detail with you.

    Use with caution and only with veterinarian's approval for dogs that are breeding, pregnant or lactating


    There is the risk of negative drug interactions between Credelio Plus and other pet Rx medications, including cyclosporine, amidarone, diltiazem, azole antifungals, and erythromycin. It is advisable to inform your veterinarian of all medications your pet is currently taking before getting the prescription and proceeding to buy Credelio Plus.

    Side Effects

    Credelio Plus side effects are uncommon, but some dogs may experience lethargy, excessive drooling, pupil dilation, weight loss, elevated blood urea nitrogen, increased urination, or diarrhea. If Credelio Plus side effects are seen, you may want to discontinue use and speak to your veterinarian again regarding full spectrum parasite protection for dogs alternatives.

    Product Code : 13571