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Advantage ii for dogs

Advantage II for Dogs (Imidacloprid / Pyriproxyfen)

Pet Size

Don't know your pet's weight?

If you can't get them on the scale, try this super simple method:

  1. Weigh yourself.
  2. Weigh yourself holding your pet.
  3. Subtract the two numbers to get their weight.

Too heavy to hold? Your vet will weigh them if you ask (or may already have it on file if you call).


No Prescription Required

  • Description

    Fleas are often the #1 nuisance for dogs, and dog owners will want an effective flea medication for dogs that they can rely on to put an end to that nuisance and all the incessant scratching that comes along with it. Advantage II for dogs is the best solution, and it’s earned its spot as one of the best flea medications for dogs these days. That’s because not only is it a good flea killer medication, but it also is able to eliminate these pests at all life stages. It kills flea eggs and larvae too, so when you give your dog his or her once-a-month application you can count on seeing long-lasting relief from fleas.

    Advantage II for dogs has the ability kill 98+% of fleas within 12 hours of being applied, and applying this quality flea medication for dogs couldn’t be any easier.


    Apply Advantage II for dogs once a month, and apply the entire contents of each application pack directly to the pet’s skin and beneath its fur right at the base of the skull / top of the neck. Apply evenly to 3 or 4 different spots in this region.


    Imidacloprid 9.10%, Pyriproxyfen 0.46%


    This topical flea medication is for external use only, and is not be used with puppies under seven weeks of age. You must also consult with your veterinarian before beginning use of Advantage with debilitated, aged, pregnant or nursing animals. Also be aware that some pets may show themselves to be sensitive to use of this product and if that's the case you should cease using Advantage immediately. Plus, if your pet is taking any other medication it is best to discuss possible interaction risks with your veterinarian before beginning use of Advantage.


    There are no known interaction risks between use of Advantage II for dogs and any other Rx pet medication but it is recommended to discuss all medications your pet is currently taking when speaking with your veterinarian about flea medication.

    Side Effects

    Side effects from use of Advantage II for dogs are uncommon, but may include skin irritation, gastrointestinal issues like vomiting, diarrhea or hypersalivation, and lethargy. If any of these symptoms continue or worsen you should see a veterinarian.

    Frequently Asked Questions about Advantage II

    What is the difference between Advantage and Advantage II?

    Advantage II contains an additional active ingredient, pyriproxyfen, which kills flea eggs and larvae in addition to adult fleas. Advantage, on the other hand, only kills adult fleas.

    What does Advantage II treat?

    Advantage II is primarily used to treat and prevent flea infestations in dogs. It kills adult fleas, flea larvae, and flea eggs.

    Does Advantage II expire?

    Yes, Advantage II does have an expiration date. It's important to check the packaging for the expiration date and not to use the product if it has expired.

    How long does Advantage II take to work?

    Advantage II starts killing fleas within 12 hours of application.

    How to apply Advantage II on dogs?

    To apply Advantage II, part the hair on your dog's back between the shoulder blades and apply the entire contents of the tube directly onto the skin. It's important to apply it to an area where your dog cannot lick it off.

    What are the side effects of Advantage II for dogs?

    Possible side effects of Advantage II for dogs include skin irritation or redness at the application site, hair loss, or behavioral changes. If you notice any unusual symptoms after applying Advantage II, consult your veterinarian.

    Does Advantage II kill ticks?

    Advantage II is primarily formulated to kill fleas and flea larvae. While it may have some effect on ticks, it's not as effective as other products specifically designed to kill ticks.

    How long does Advantage II last?

    Advantage II provides protection against fleas for up to four weeks after application.

    How often can you apply Advantage II for dogs?

    Advantage II can be applied once a month for continuous flea protection. However, always follow the instructions provided by your veterinarian or on the product packaging.

    Is Advantage II waterproof?

    Yes, once Advantage II is applied and has had time to dry, it becomes waterproof. Your dog can swim or be bathed without affecting its effectiveness.

    Product Code : 12625