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Vetmedin

Vetmedin
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Use: Vetmedin-Adult Dogs

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Vetmedin (pimobendan) is supplied as oblong half-scored chewable tablets containing 1.25 or 5 mg pimobendan per tablet. Pimobendan, a benzimidazole-pyridazinone derivative, is a non-sympathomimetic, non-glycoside inotropic drug with vasodilatative properties. Pimobendan exerts a stimulatory myocardial effect by a dual mechanism of action consisting of an increase in calcium sensitivity of cardiac myofilaments and inhibition of phosphodiesterase (Type III). Pimobendan exhibits vasodilating activity by inhibiting phosphodiesterase III activity.

 

Vetmedin should be administered orally at a total daily dose of 0.23 mg/lb (0.5 mg/kg) body weight, using a suitable combination of whole or half tablets. The total daily dose should be divided into 2 portions that are not necessarily equal, and the portions should be administered approximately 12 hours apart (i.e., morning and evening). The tablets are scored and the calculated dosage should be provided to the nearest half tablet increment.
 
DOSAGE
 
 
Vetmedin should be administered twice daily 12 hours apart and based on the following guidelines: 
 
1.25mg pill
 
Weight - 5lbs (2.5kg) / daily dosage - 1.25mg  / one 1/2 pill every 12 hours 
Weight - 8.25lbs (3.75kg) / daily dosage - 1.875mg  / one full pill and 1/2 pill 12 hours later 
Weight - 11lbs (5kg) / daily dosage - 2.50mg  / one full pill and another full pill 12 hours later 
Weight - 16lbs (7.5kg) / daily dosage - 3.75mg  / 1.5 pill and another 1.5 pill 12 hours later 
Weight - 22lbs (10kg) / daily dosage - 5.06mg  / 2 pills and then another 2 pills 12 hours later 
 
5.0mg pill
 
Weight - 22lbs (10kg) / daily dosage - 1.25mg  / one 1/2 pill every 12 hours 
Weight - 33lbs (15kg) / daily dosage - 7.59mg  / one full pill and 1/2 pill 12 hours later 
Weight - 44lbs (20kg) / daily dosage - 10.12mg  / one full pill & another full pill 12 hours later 
Weight - 66lbs (30kg) / daily dosage - 15.18mg  / 1.5 pill and another 1.5 pill 12 hours later 
Weight - 88lbs (40kg) / daily dosage - 20.24mg  / 2 pills and then another 2 pills 12 hours later
 

 

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